SATURDAY, SEPTEMBER 11th, 2021

All times in Central European Summer Time (CEST)

13:00-14:00

POSTER SESSION: meet the poster presenter

14:00 - 15:00

SHORT COMMUNICATIONS III

Chaired by: Kathrin Reetz and Jean-Marc Burgunder

1. FAN1 Controls CAG Repeat Expansion in Huntington's Disease by Dual Functions, MLH1 Retention and Nuclease Activity

Joseph Hamilton

2. Striatal Procedural Memory-Induced Transcriptome and Epigenome are Severely Impaired in Huntington’s Disease Mice

Rafael Alcalá-Vida

3. A New In Vivo and In Vitro Single-Cell Atlas of Developing Medium Spiny Neurons to Guide Future Improvements for Huntington Disease Cell-Replacement Therapies and Disease Modelling

Vittoria Bocchi

4. Huntingtin-Mediated Axonal Transport Requires Arginine Methylation by PRMT6

Alice Migazzi

5. The ‘Hold me Tight’ Relationship Program for Couples Facing Huntington’s Disease
Lucienne van der Meer

15:00 - 16:00

PARALLEL SESSIONS

 

Digital Technologies to Advance Assessment

and Care in HD
Chaired by Alzbeta Mühlbäck and Monica Busse

 

Sleep, circadian rhythm and metabolism in HD

Chaired by: Patrick Weydt and Asa Petersen

1. Introduction to the session: Landscape View of    the Field (10 min)

Monica Busse

2. IDEA-FAST (15 min)

Ralf Reilmann

3. HEALTHe-RND overview (10 min)

Pearl van Lonkhuizen

4. DOMINO-HD overview (15 min)
Philippa Morgan-Jones

5. Panel Discussion: Ethical & practical challenges (10min)

All speakers and chairs

 

1. Introduction to the topic by the chairs  

2. Sleep and metabolism in Huntington disease (15 min)

Roger Barker

3. Clock genes and circadian rhythm (15 min)

Charalambos P. Kyriacou

 4. Targeting cholesterol metabolism as a therapy for Huntington disease (15 min)

Sandrine Betuing

5. Summary and practical tips (15 min)

 

16:00 - 16:15

BREAK

16:15 - 17:45

 

PLENARY SESSION IV: Upcoming Clinical Trials*

*This Session involves content created by Industry (in agreement with the EHDN Program Committee).
Different Pharma industries have the opportunity to present their current trials, results and upcoming
projects.

17:45 - 18:00

BREAK

18:00 - 18:45

KEYNOTE SESSION II: Outlook

Chaired by: Dina de Sousa and Giorgos Papantoniou

New staging system in HD extending the window of testing and treatment

Cristina Sampaio (30 min)

Q&A (15 min) 

18:45 - 19:40

ROUND-UP and Goodbye for the day

Chaired by: Anne Rosser and Jean-Marc Burgunder

Historical perspective (30 min) with Q&A (15 min)

Tom Bird

Goodbye (10 min)

Host Anne Rosser and Jean-Marc Burgunder with Tom Bird, Astri Arnesen and Matthew Ellison